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Rev. otorrinolaringol. cir. cabeza cuello ; 68(2): 124-130, ago. 2008. ilus, tab
Article in Spanish | LILACS | ID: lil-503435

ABSTRACT

Introducción: La rinosinusitis crónica (RSC) es un cuadro inflamatorio en el que las bacterias juegan un rol importante. Las exacerbaciones agudas de rinosinusitis crónica (EARSC) en pacientes posoperados no son infrecuentes. Sin embargo, su manejo es complejo debido a la aparición de nuevos agentes y el aumento de la resistencia a antibióticos. Objetivo: Desarrollar una técnica de toma de muestra en cavidades paranasales, que permita caracterizar a los agentes involucrados en EARSC en pacientes posoperados. Material y método: Se recluta ron 32 pacientes posoperados. Se realizó aspirado de seno maxilar bajo visión endoscópica. Las muestras fueron cultivadas para aerobios, anaerobios y hongos. Resultados: Se enviaron 50 muestras a cultivo, en 46 de ellas se aislaron gérmenes (92%), de los cuales 44 fueron aerobios. En 7 de las muestras se aislaron anaerobios, y en 2 se obtuvo cultivo positivo para hongos. La resistencia a betalactámicos fue de 48,2%, observándose 36% de resistencia a lo menos a dos familias de antibióticos. Discusión y conclusiones: Nuestro estudio es el primero a nivel nacional en caracterizar a los agentes involucrados en EARSC en pacientes poscirugía endoscópica nasal. Los resultados obtenidos, posicionan a los cultivos endoscópicos como una excelente herramienta clínica para estudiar las EARSC.


Introduction: Chronic rhinosinusitis (CRS) is an inflammatory condition where bacteria play an important role. Acute exacerbations of chronic sinusitis (AECS) in patients who underwent endoscopic sinus surgery (EES) are not infrequent. Treatment of these exacerbations is complex due to the emergence of new agents and to an increase in bacterial resistance. Therefore, it is important to develop methods to culture and identify these agents and their antimicrobial resistance and sensibilities. Aim: To develop a technique for recovery of pathogens in the paranasal sinuses of patients with AECS after EES. Material and Method: 32 patients that had undergone EES were recruited. Aspiration of the maxillary sinus under direct endoscopic vision was performed. Samples obtained were sent for aerobic, anaerobia and fungal cultures. Results: Of the 50 samples collected, 46 were positive. Of these, 44 cultured aerobes, 7 cultured anaerobes, and 2 cultured fungi. The resistance to betalactamic antibiotics was 48.2% with at least 36% resistance to two different types of antibiotics. Conclusion: This is the first report in Chile of the microorganisms involved in AECS after EES. The results suggest that the sampling method described here is a useful tool for the study of patients with AECS.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged, 80 and over , Rhinitis/microbiology , Paranasal Sinuses/surgery , Sinusitis/microbiology , Anti-Bacterial Agents/therapeutic use , Bacteria, Aerobic/isolation & purification , Bacteria, Anaerobic/isolation & purification , Endoscopy , Acute Disease , Chronic Disease , Prospective Studies , Drug Resistance, Bacterial , Fungi/isolation & purification , Culture Media , Postoperative Period , Rhinitis/drug therapy , Paranasal Sinuses/microbiology , Sinusitis/drug therapy
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